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Best enzymes - September 2025

Last Updated - September 22, 2025

1
Best Choice

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

THORNE

THORNE - Advanced Digestive Enzymes (Formerly Bio-Gest) - Blend of Digestive Enzymes to Aid Digestion* - Gut Health Support with Pepsin, Ox Bile, Pancreatin - 180 Capsules - 90 Servings

THORNE

$53.00

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Main highlights
- Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the #1 recommended clinical brand by health-care practitioners
- Support for Indigestion: Benefits individuals who have occasional indigestion, food sensitivities, gallbladder removal, or who have overused antacids*
- Promotes Nutrient Absorption: Benefits absorption of vitamins, minerals, and other nutrients*
- Promotes Digestion: Can help ease digestive discomfort that may occur after a meal heavy in fat or red meat, when enjoying foods that cause extra gas and bloating, or when partaking in an occasional overindulgence
- Comprehensive Formula: A blend of hydrochloric acid, pepsin, pancreatin, and ox bile
$53.00
2

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Unipomme

Pancreatic Enzymes for Dogs - 10x Pancreatin Formula for EPI Dog - Pancretase Digestive Enzymes Tablets for Pet Pancreatic Concerns, Supports Buddy Digestive Stress, Healthy Weight Management

Unipomme

$39.99

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Main highlights
- Trusted by Vets, Loved by Pets: Our pancreatic enzyme Tablets for dogs undergoes rigorous testing to ensure safety and effectiveness. Specially formulated to support digestion and promote optimal gut health, it helps your beloved companion stay happy, healthy, and full of life
- Triple-Enzyme Support for Optimal Nutrient Absorption - Our Pancreatic Enzymes for Dogs with amylase, protease, and lipase, this enzyme supplement mimics the natural digestive process, making food easier to digest and nutrients easier to absorb. The result? Healthier weight, better stools, a shinier coat, and more tail-wagging joy at mealtime
- High-Potency Formula for Maximum Digestive Support - With 10X-strength porcine pancreatic enzymes, our formula delivers the essential digestive support your dog needs. It helps break down fats, proteins, and carbohydrates efficiently, reducing bloating, discomfort, and nutrient loss—so every meal fuels their health, not their struggles
- Easy to Use - Ideal for pets over six weeks of age, our digestive enzymes for dogs and cats are perfect for every meal—just mix this low-odor, acetone-free Tablets into your dog’s moist food and let it sit for 15 -20 minutes. Safe for all breeds and life stages, from playfully to aging seniors, it’s the hassle-free way to support their digestive health
- Designed for Pets Struggling with EPI - Does your dog battle constant weight loss, loose stools, or poor appetite? Watching them struggle can be heartbreaking. Our Pancreatic Enzymes support pets with EPI and digestive issues, helping them absorb nutrients properly so they can regain strength, maintain a healthy weight, and feel like their old selves again. Enjoy a happy, thriving companion by your side
$39.99
3
Best Value

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Pure Encapsulations

Pure Encapsulations Digestive Enzymes Ultra - Vegetarian Digestive Enzyme Supplement to Support Protein, Carb, Fiber, and Dairy Digestion* - 90 Capsules

Pure Encapsulations

$36.20

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Main highlights
- Supports Digestion: Facilitates the normal breakdown of proteins, peptides, polysaccharides and disaccharides; assists with dairy, fiber, and protein digestion*
- Pure Difference: What we leave out matters, too; Pure Encapsulations products are free from common allergens, artificial or unnecessary ingredients, and GMOs
- Nutrient Absorption: Contains a mixture of vegetarian enzymes developed to support nutrient bioavailability and absorption; supports digestion*
- Digestive Enzymes: Offers a broad-spectrum combination of vegetarian digestive enzymes designed to provide optimal activity across a wide pH range
- Dairy Enzyme Blend: This vegetarian enzyme blend supports digestion of dairy, sugar, lactose, and certain complex carbs; supports relief from occasional gas or bloating
$36.20
4

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Micro Ingredients

Super Enzymes with Prebiotics & Probiotics, 240 Veggie Capsules | High Potency Digestive Enzymes For Women & Men | Probiotic, Bromelain, Psyllium Husk & More | Immune & Gut Health Support

Micro Ingredients

$19.99

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Main highlights
- Premium non-GMO supplements. Made without soy, dairy, gluten, wheat, and tree nuts. Ingredients must pass a 3rd party lab test to ensure our product is safe, pure, and potent.
- Micro Ingredients offers a high potency Super Enzymes+ formula that delivers a powerful synbiotic complex featuring 20 digestive enzymes, 200mg of prebiotics, and 1 billion CFUs of probiotics per serving.
- Enjoy comprehensive support with targeted ingredients for combating occasional gas and bloating while promoting a regular digestive process.
- Each bottle contains 240 natural vegetarian capsules. An all-in-one formula that includes a diverse blend of Amylase, Papain, Bromelain, Psyllium Husk, Inulin, Lactobacillus, Bifidobacterium and more.
- A full spectrum blend of enzymes, prebiotics, and probiotics designed to help break down carbohydrates, proteins, fiber, fats, and lactose. Supports nutrient absorption, digestive comfort, and a balanced gut microbiome.
$19.99
5

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Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Physician's CHOICE

Physician's CHOICE Digestive Enzymes - Multi Enzymes, Organic Prebiotics & Probiotics for Digestive Health & Gut Health - Meal Time Discomfort Relief & Bloating - Dual Action Approach - 90 CT

Physician's CHOICE

$26.97

More Details
Main highlights
- Science Backed - Our Digestive Enzyme Probiotics are crafted based on scientific research. We have partnered with expert physicians to help review our products & research. We strive to educate & help you with informed decisions regarding your health.
- Safety Assured Standard of Quality: Our Digestive Enzymes are 3rd-party tested for purity and potency. Each bottle is manufactured with love & care in the USA with strict quality control - using imported and domestic ingredients.
- Probiotics that Survive the Gut: Formulated with 3 soil-based probiotic strains - specifically selected due to their ability to survive the harsh gut environment. Along with Organic Prebiotics that fuel the growth of healthy bacteria in the gut.
- Dual Action Relief: Our powerful digestive enzymes aid with breaking down food while the prebiotics & probiotics promote digestive function in the gut. They work synergistically to provide relief from mealtime discomfort.
- Beat the Bloat & Say Goodbye to Meal Time Discomfort: 16 beneficial enzymes that digest proteins, carbs, fruits, veggies, beans, dairy, & fats to cover all diets. With SBO Probiotics & Prebiotics to aid digestion further - Your New Meal Time Hack! Same great product you love, with a new look. Packaging May Vary!
$26.97

Best enzymes - September 2025

THORNE - Advanced Digestive Enzymes (Formerly Bio-Gest) - Blend of Digestive Enzymes to Aid Digestion* - Gut Health Support with Pepsin, Ox Bile, Pancreatin - 180 Capsules - 90 Servings

Pancreatic Enzymes for Dogs - 10x Pancreatin Formula for EPI Dog - Pancretase Digestive Enzymes Tablets for Pet Pancreatic Concerns, Supports Buddy Digestive Stress, Healthy Weight Management

Pure Encapsulations Digestive Enzymes Ultra - Vegetarian Digestive Enzyme Supplement to Support Protein, Carb, Fiber, and Dairy Digestion* - 90 Capsules

Super Enzymes with Prebiotics & Probiotics, 240 Veggie Capsules | High Potency Digestive Enzymes For Women & Men | Probiotic, Bromelain, Psyllium Husk & More | Immune & Gut Health Support

Physician's CHOICE Digestive Enzymes - Multi Enzymes, Organic Prebiotics & Probiotics for Digestive Health & Gut Health - Meal Time Discomfort Relief & Bloating - Dual Action Approach - 90 CT

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