Advertising Disclosure

Best acetaminophens - August 2025

Last Updated - August 6, 2025

1
Best Choice

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

TIME-CAP LABS, INC.

TIME-CAP LABS, INC. Timely Acetaminophen 650 MG - 400 Caplets - Extended Release - Joint Pain Relief, Pain Reliever & Arthritis Pain Relief

TIME-CAP LABS, INC.

$22.30

$23.50
(5% Off)

More Details
Main highlights
- Relieve Minor Aches and Pains ... Toothache? Backache? Acetaminophen relieves minor aches and pains due to headache, backache, toothache, the common cold, minor pain of arthritis, muscular aches, and premenstrual and menstrual cramps.
- One in Every Medicine Cabinet ... Make sure every medicine cabinet and first-aid kit has these great pain relief tablets. 400 caplets are plenty enough to provide long-term relief for the family.
- Let That Fever Subside ... Dealing with a fever? Acetaminophen temporarily reduces fever, and relieves those aches and pains caused by minor pain of arthritis.
- Highest Quality ... These OTC medications & treatments provide the same efficacy as your usual branded extra strength acetaminophen.
- An Easy Way to Be Pain-Free … Find prolonged relief in a bottle of this Arthritis Pain Relief Acetaminophen 650mg. Take as directed on the bottle.
$22.30
$23.50 (5% Off)
2

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Amazon Basic Care

Amazon Basic Care Acetaminophen Extended-Release Tablets, 650 mg, Arthritis Pain, 400 Count

Amazon Basic Care

$22.22

More Details
Main highlights
- TEMPORARY PAIN RELIEF: This product may also be used to temporarily relieve other minor aches and pains due to: muscular aches, backache, premenstrual and menstrual cramps, the common cold, headache, toothache.
- PUSH & TURN CAP: The container has a child-resistant cap. This product is a pain reliever and fever reducer for adults. Under 18 years of age, ask a doctor.
- PURPOSE: Amazon Basic Care Acetaminophen Extended-Release Tablets, 650 mg is a pain reliever and fever reducer that can be used for the temporary relief of minor pain of arthritis.
- ASPIRIN FREE, GLUTEN FREE: Extended release caplets (capsule-shaped tablets) each provide 650 mg of acetaminophen, pain reliever and fever reducer, and contain no aspirin. Effective for minor arthritis pain. This product is gluten free.
- ACTIVE INGREDIENT: Amazon Basic Care Acetaminophen Extended-Release Tablets, 650 mg active ingredient is acetaminophen 650 mg,. Compare to the active ingredient in Tylenol 8HR Arthritis Pain.
$22.22
3

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Amazon Basic Care

Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, Pain Reliever/Fever Reducer, 500 Count (Packaging may vary)

Amazon Basic Care

$10.79

More Details
Main highlights
- USE: Acetaminophen may be used as a pain reliever and fever reducer for adults and children 12 years and over
- Product may be manufactured in India or U.S.
- PAIN: Pain may begin with an injury or illness, but could also originate with anything from a bad mattress to arthritisACUTE PAIN: Acute pain acts as an alarm such as with a bee sting or stubbing your toe and can last for a few moments or for longer
- ACTIVE INGREDIENT: Amazon Basic Care Extra Strength Pain Relief's active ingredient is Acetaminophen, 500 mg, which compares to the active ingredient of Extra Strength Tylenol CapletsAmazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, temporarily relieves minor aches and pains due to: the common cold, headache, backache, minor pain of arthritis, toothache, muscular aches, and premenstrual and menstrual cramps also temporarily reduces fever
$10.79
4

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

GoodSense

GoodSense Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, 500 Count

GoodSense

$9.99

More Details
Main highlights
- USE: Acetaminophen may be used as a pain reliever and fever reducer for adults and children 12 years and over
- PAIN: Pain may begin with an injury or illness, but could also originate with anything from a bad mattress to arthritis
- GoodSense Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, temporarily relieves minor aches and pains due to: the common cold, headache, backache, minor pain of arthritis, toothache, muscular aches, and premenstrual and menstrual cramps. It also temporarily reduces fever
- ACUTE PAIN: Acute pain acts as an alarm such as with a bee sting or stubbing your toe and can last for a few moments or for longer
- ACTIVE INGREDIENT: GoodSense Extra Strength Pain Relief's active ingredient is Acetaminophen, 500 mg, which compares to the active ingredient of Extra Strength Tylenol Caplets
$9.99
5
Best Value

✖
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

Amazon Basic Care

Amazon Basic Care Rapid Release Acetaminophen Caplets 500 mg, Extra Strength Pain Reliever and Fever Reducer, 400 Count

Amazon Basic Care

$17.63

$18.89
(6% Off)

More Details
Main highlights
- GLUTEN FREE: This pain reliever and fever reducer is free of gluten, aspirin and caffeine.
- FOR ADULTS: Amazon Basic Care Rapid Release Pain Relief, Acetaminophen Caplets 500 mg contain an extra strength pain reliever and fever reducer for adults and children ages 12 years and over
- EXTRA STRENGTH: These extra strength caplets are made for fast relief, with 500 mg of acetaminophen; package features a child-resistant cap
- EFFECTIVE: This product temporarily relieves minor aches and pains due to headache, muscular aches, backache, minor pain of arthritis, the common cold, toothache and premenstrual and menstrual cramps. Also temporarily reduces fever.
- ACTIVE INGREDIENT: Amazon Basic Care Rapid Release Acetaminophen 500 mg Caplets active ingredient is 500 mg of acetaminophen, a pain reliever and fever reducer. Compare to Tylenol Extra Strength Rapid Release Gels active ingredient.
$17.63
$18.89 (6% Off)

Best acetaminophens - August 2025

TIME-CAP LABS, INC. Timely Acetaminophen 650 MG - 400 Caplets - Extended Release - Joint Pain Relief, Pain Reliever & Arthritis Pain Relief

Amazon Basic Care Acetaminophen Extended-Release Tablets, 650 mg, Arthritis Pain, 400 Count

Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, Pain Reliever/Fever Reducer, 500 Count (Packaging may vary)

GoodSense Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, 500 Count

Amazon Basic Care Rapid Release Acetaminophen Caplets 500 mg, Extra Strength Pain Reliever and Fever Reducer, 400 Count

You may also like...

Tylenol Extra Strength Acetaminophen Rapid Release Gels, Extra Strength Pain Reliever & Fever Reducer, Gelcaps with Laser-Drilled Holes, 500 mg Acetaminophen, 100 ct

HealthA2Z® Extra Strength Pain Relief | Acetaminophen 500mg | Contains No Aspirin | Fever Reducer | Pain Reliever (500 Count (Pack of 1))

Timely Acetaminophen 500mg - 500 Caplets - Extra Strength Pain Relief - Compared to the active ingredient in Extra Strength - Menstrual Cramps, Fever Reducer, Minor Pain of Arthritis

Tylenol Regular Strength Tablets with 325 mg of Acetaminophen, Fever Reducer & Pain Reliever for Headache, Backache, Muscle Aches, Joint Pain & Menstrual Cramps, 100 ct

Amazon Basic Care Acetaminophen Extended-Release Tablets, 650 mg, 100 Count (Packaging may vary)

Amazon Basic Care Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, Pain Reliever/Fever Reducer, 100 Count (Packaging may vary)

GoodSense Extra Strength Pain Relief, Acetaminophen Caplets, 500 mg, 50 Count

GenCare - Acetaminophen 500mg Extra Strength Pain Relief (300 Caplets) - Multi Symptom Pain Reliever for Headache, Sinus, Arthritis, Back Pain Muscle Ache, Toothache, Fever Reducer, Migraine

NUVICARE Acetaminophen 500mg Extra Strength Pain Relief - Compare to Tylenul Extra Strength Pain Reliever & Fever Reducer - 500mg Tablets for Adults for Headaches (100 Caplets)

GeriCare Extra Strength Acetaminophen Pain Relief Fever Reducer Tablets, Strength 500mg Tablet | Joint, Muscle, Arthritis, Back Pain Relief 100 Count (Pack of 1)

Sign up and get exclusive special deals